William Ford De Saussure (born February 22, 1792) was a Democratic politician from South Carolina who served as a United States senator in the mid-nineteenth century. Representing the state of South Carolina, he held office in the U.S. Senate as a member of the Democratic Party and is recorded as a historical member of Congress. His tenure in the Senate places him among the antebellum legislators who served in the years leading up to the American Civil War.
De Saussure served a single term in the United States Senate, with his service dated from January 1, 1852, to March 3, 1853. During this period, he held the role of senator for South Carolina, without a designated congressional district, as senators represent their states at large. Although details of his committee assignments, legislative initiatives, and other offices are not provided in the available record, his time in the Senate from 1851 to 1853 marks his principal known contribution to national political life.
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